Synthesis and reactivity of 4-(trifluoromethyl)azetidin-2-ones
نویسندگان
چکیده
منابع مشابه
SYNTHESIS OF 3-ARYLMETHYL-4- THIAZOLIDINE-CARBOXYLIC ACID-2-ONES AND 2-THIONES
Barium salts of dibenzylidene cystines 8a-c were obtained from the reaction of Lcystine with benzaldehyde or its derivatives in the presence of barium hydroxide. Their reduction with zinc and hydrochloric acid in methanol yielded the Narylmethylcysteines ?9a-c?. These can, in turn, be converted by esterification into the methyl esters ?10 a-c. ?Reaction of N, N'-carbonyl diimidazole (Im C...
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Synthesis of 2-[2-(2,6-dichlorophenyl)amino]phenylmethyl-3-[4-(2-substitutedphenyl-4-oxo-thiazolidinyl)aryl]-6-bromo quinazolin-4(3H)ones VIa-j have been achieved from the starting material 2-[(2,6-dichlorophenyl)amino] phenylacetic acid I to benzoxazine III, Further reaction with p-phenylindiamine and substituted aromatic aldehyde gave 2-[2-(2,6-dichlorophenyl)amino]phenyl methyl-3-(4-aminoary...
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Synthesis of 2-[2-(2,6-dichlorophenyl)amino]phenylmethyl-3-[4-(2-substitutedphenyl-4-oxo-thiazolidinyl)aryl]-6-bromo quinazolin-4(3H)ones VIa-j have been achieved from the starting material 2-[(2,6-dichlorophenyl)amino] phenylacetic acid I to benzoxazine III, Further reaction with p-phenylindiamine and substituted aromatic aldehyde gave 2-[2-(2,6-dichlorophenyl)amino]phenyl methyl-3-(4-aminoary...
متن کاملsynthesis of 3-arylmethyl-4- thiazolidine-carboxylic acid-2-ones and 2-thiones
barium salts of dibenzylidene cystines 8a-c were obtained from the reaction of lcystine with benzaldehyde or its derivatives in the presence of barium hydroxide. their reduction with zinc and hydrochloric acid in methanol yielded the narylmethylcysteines ?9a-c?. these can, in turn, be converted by esterification into the methyl esters ?10 a-c. ?reaction of n, n'-carbonyl diimidazole (im co...
متن کاملSynthesis and Pharmacological Evaluation of Azetidin-2-ones and Thiazolidin-4-ones Encompassing Benzothiazole
Various 7-chloro-6-fluoro-2-arylidenylaminobenzo(1,3)thiazole (2a-h) have been synthesized by the condensation of 7-chloro-6-fluoro-2-aminobenzo(1,3)thiazole (1) with different aromatic aldehydes. The Schiff's bases on reaction with acetyl chloride, chloroacetyl chloride and phenyl acetyl chloride yielded 1-(7-chloro-6-fluorobenzothiazol-2-yl)-3,4-substituted-aryl-azetidin-2-ones (3a-x). Simila...
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ژورنال
عنوان ژورنال: Monatshefte für Chemie - Chemical Monthly
سال: 2018
ISSN: 0026-9247,1434-4475
DOI: 10.1007/s00706-017-2134-2